The effect of Rosemary and Cinnamon extracts on blood glucose levels in albino rats with Alloxan-induced diabetes

Abstract

Background: Herbs have long been recognized for their medicinal properties, with rosemary and cinnamon noted for their health benefits. Rosemary is used for treating respiratory infections and has antioxidant and antimicrobial effects, while cinnamon is known for its antispasmodic and antimicrobial properties.

Objective : This study aimed to evaluate the effects of rosemary and cinnamon extracts on blood glucose levels in diabetic albino rats.

Methodology : Thirty male rats were divided into six groups, with five groups induced with diabetes using Alloxan. Group I served as the normal control, while Group II was the diabetic control. Groups III and IV received 400 mg/day of rosemary and cinnamon extracts, respectively, Group V received a combination of both, and Group VI received glibenclamide as a positive control. After eight weeks  .  

Results: The results showed that both extracts significantly reduced blood glucose levels (p < 0.0001), with reductions of 49.9% for rosemary and 58.8% for cinnamon. The combination of both extracts led to a 70.8% reduction in blood glucose levels (p < 0.0001).

Conclusion: The individual use of rosemary and cinnamon extract has a significant effect in lowering blood glucose but the using of combined extract has more significant effect in lowering blood glucose.